CRISPR adaptive immunity systems of prokaryotes
Identifieur interne : 002396 ( Main/Exploration ); précédent : 002395; suivant : 002397CRISPR adaptive immunity systems of prokaryotes
Auteurs : K. S. Pougach [Russie] ; A. V. Lopatina [Russie] ; K. V. Severinov [Russie]Source :
- Molecular Biology [ 0026-8933 ] ; 2012-04-01.
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Abstract
Abstract: CRISPR (clustered regularly interspaced short palindromic repeats) systems were found in the genomes of many eubacteria and the vast majority of archaea. Their unique feature is that CRISPR-mediated immunity is adaptive and can be programmed to protect cells against mobile genetic elements. The review describes the general principles of CRISPR-mediated immunity and characterizes the CRISPR systems of various microorganisms.
Url:
DOI: 10.1134/S0026893312020136
Affiliations:
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